Sun exposure increases appetite in males, according to a new study from Tel Aviv University. Does not increase appetite in females.
A study conducted in laboratory models revealed differences between males and females in the activation of metabolic mechanisms.
Researchers explain that in males of both animal and human species. Exposure to sunlight activates a protein called p53. Repairs DNA damage in the skin caused by sun exposure.
p53 causes the body to produce a hormone called ghrelin, which stimulates appetite. In females, Estrogen blocks the interaction between p53 and ghrelin. It does not stimulate the urge to eat after sun exposure.
The groundbreaking study was led by Professor Carmit Levy and PhD student Shivang Parikh in the Department of Human Genetics and Biochemistry at TAU’s Sackler School of Medicine.
Israel has collaborated with many researchers around the world. This news was published in the famous journal Nature Metabolism. The study is based on epidemiological data collected in a year-long survey of the eating habits of approximately 3,000 Israelis.
A laboratory model included students’ self-reports of time spent in the sun combined with the results of genetic studies.
Laboratory studies have shown that in both humans, the skin is a major regulator of energy and appetite (metabolism).
Researchers explain that there are significant physiological differences between males and females and their behavior affects health. However, Whether the sexes respond differently to environmental triggers, such as exposure to the sun’s UV rays, has not yet been determined.
Professor Levy: “We observed a difference between men and women after sun exposure. Men have been found to eat more than women because their appetites have increased. The study is the first gender-specific clinical study of UV exposure.
For the first time, a molecular link between UV exposure and appetite has been mapped. Gender-dependent medical studies are particularly complex. Because double the number of participants is needed to find statistically significant differences.
Professor. Levy concludes: “Because people give up their fur visions; The skin, the largest organ in the body, receives many signals from the environment. The protein p53, found in the skin, further repairs DNA damage caused by sun damage.
When winter is over, we are in the sun. Perhaps in preparation for mating season. UV-based therapies have potential for human metabolic and metabolic disorders such as anorexia nervosa. UV-based therapies are an exciting basis for research.”